What Factors Impact the Iontophoresis-Based Treatment?

Iontophoresis is becoming a revolutionary way to treat hyperhidrosis. This condition consists of sweating heavily, and it is a bothering symptom in various body parts, including hands and feet. Iontophoresis is a technique designed to create ions out of water molecules and other soluble substances. After the target substance is converted into polarized particles with an electrical charge, a mild electrical current creates an electromagnetic gradient in the skin that allows molecules to migrate to deeper layers. This is a non-invasive method to deliver certain substances to deep tissues or the bloodstream.

However, the success of an iontophoresis-based therapy for hyperhidrosis depends on various factors, including skin-related factors and others that would depend on the procedure and the adjustments of the device itself.

What factors influence iontophoresis as a treatment?

We can name at least seven different factors that influence the results of iontophoresis. They are as follows:

Is it going to cure hyperhidrosis?

The principles of iontophoresis are not new, but its application in the medical field is starting to develop. Thus, there is not a fixed concentration of the solution or dose of the electrical current recommended for each condition and to favor the absorption of each drug. Still, it is an effective treatment for hyperhidrosis, and even though it takes time and requires treatment sessions, the majority of patients with this condition report a significant improvement of their symptoms and feel satisfied with their results.

We still do not fully understand the full extent and application of iontophoresis, but so far, it’s turning into a promising way to deliver drugs without invasive procedures or side effects. It is an effective way to control hyperhidrosis and an exciting field of ongoing clinical research.



Dr. Gary C. Anderson M.D is a Surgeon who specializes in the treatment of hyperhidrosis. During the past 20 years, he has performed over 2000 sympathectomy procedures on patients with sweating of the underarms, hands, face, scalp or blushing.